Blacks and whites have a similar prevalence of reduced left ventricular ejection fraction in the general population: The Dallas Heart Study (DHS)

David W. Markham, Daniel L. Dries, Louise P. King, David Leonard, Clyde W. Yancy, Ronald M. Peshock, Du Wayne Willett, Richard S. Cooper, Mark H. Drazner*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Background: The objective of the study was to evaluate racial differences in the prevalence of left ventricular (LV) dysfunction. Few data compare the relative frequency of reduced LV ejection fraction (EF) (LVEF) in blacks and whites. Because of the higher prevalence of risk factors for heart failure in blacks, including hypertension, obesity, and LV hypertrophy, we hypothesized that LV dysfunction would also be more common in this ethnic group. Methods: In the DHS, a probability-based sample of Dallas County, we performed cardiac magnetic resonance imaging on 1335 black and 858 white participants aged 30 to 67 years to measure LVEF and volumes. We compared the prevalence of reduced LV EF and distribution of ventricular volumes in the 2 ethnic groups. Results: The prevalence of a reduced LVEF, whether defined as <50%, <55%, or <60%, did not appear to be different between black versus white women (P ≥ .7 for each) or men (P ≥ .4 for each). Similar findings were seen using a recently defined sex-specific threshold (men <55% and women <61%) for low EF (P = .1). Mean LV end-diastolic and end-systolic volumes indexed to body surface area were also comparable in black and white men (P ≥ .3) and women (P ≥ .1). Conclusions: Despite having a higher prevalence of risk factors for heart failure, blacks as compared with whites did not have a higher prevalence of reduced LVEF in the general population.

Original languageEnglish (US)
Pages (from-to)876-882
Number of pages7
JournalAmerican heart journal
Volume155
Issue number5
DOIs
StatePublished - May 2008

Funding

The DHS is funded by a center grant from the Donald W. Reynolds Foundation, Las Vegas, NV. Dr. Markham was supported by the NIH Clinical Research Scholars (K12) Program.

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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