Blood pressure and sodium-lithium countertransport: Findings in population-based surveys

Richard Cooper*, Maurizio Trevisan, David Ostrow, Christopher Sempos, Jeremiah Stamler

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


A total of 448 individuals ranging in age from 11 to 72 years were studied in a series of seven population-based surveys. Although the relationship was positive in all surveys, a significant correlation was noted between sodium-lithium countertransport and blood pressure in only three of the seven. Hypertensives as a group had significantly higher levels of countertransport than did those with a normal blood pressure. In stepwise regression analysis, however, entering weight into the equation eliminated a significant predictive effect of countertransport. Red cell sodium concentration and membrane leak did not bear any significant relationship to blood pressure. The association between countertransport and blood pressure appears to be weaker in the general population than previously reported for case-control studies.

Original languageEnglish (US)
Pages (from-to)467-471
Number of pages5
JournalJournal of hypertension
Issue number5
StatePublished - Oct 1984


  • Blood pressure
  • Countertransport
  • Hypertension
  • Sodium

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

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