BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way

Catherine A. Reinke; Richard W. Carthew

doi:10.1016/j.devcel.2008.07.015

BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way

Catherine A. Reinke, Richard W. Carthew^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Short survey › peer-review

6 Scopus citations

Abstract

Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.

Original language	English (US)
Pages (from-to)	174-175
Number of pages	2
Journal	Developmental Cell
Volume	15
Issue number	2
DOIs	https://doi.org/10.1016/j.devcel.2008.07.015
State	Published - Aug 12 2008

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)
Molecular Biology
Cell Biology
Developmental Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.devcel.2008.07.015

Cite this

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title = "BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way",

abstract = "Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.",

author = "Reinke, {Catherine A.} and Carthew, {Richard W.}",

year = "2008",

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AU - Reinke, Catherine A.

AU - Carthew, Richard W.

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N2 - Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.

AB - Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.

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JO - Developmental Cell

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BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way

Abstract

ASJC Scopus subject areas

UN SDGs

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