BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way

Catherine A. Reinke, Richard W. Carthew*

*Corresponding author for this work

Research output: Contribution to journalShort survey

5 Scopus citations

Abstract

Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.

Original languageEnglish (US)
Pages (from-to)174-175
Number of pages2
JournalDevelopmental Cell
Volume15
Issue number2
DOIs
Publication statusPublished - Aug 12 2008

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ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

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