BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way

Catherine A. Reinke, Richard W Carthew*

*Corresponding author for this work

Research output: Contribution to journalShort survey

5 Citations (Scopus)

Abstract

Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.

Original languageEnglish (US)
Pages (from-to)174-175
Number of pages2
JournalDevelopmental Cell
Volume15
Issue number2
DOIs
StatePublished - Aug 12 2008

Fingerprint

MicroRNAs
Heart Neoplasms
Cell Differentiation
Therapeutics

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology

Cite this

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title = "BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way",
abstract = "Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.",
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}

BMP Signaling Goes Posttranscriptional in a microRNA Sort of Way. / Reinke, Catherine A.; Carthew, Richard W.

In: Developmental Cell, Vol. 15, No. 2, 12.08.2008, p. 174-175.

Research output: Contribution to journalShort survey

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AU - Carthew, Richard W

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AB - Aberrant microRNA (miRNA) expression correlates with human diseases such as cardiac disorders and cancer. Treatment of such disorders using miRNA-targeted therapeutics requires a thorough understanding of miRNA regulation in vivo. A recent paper in Nature by Davis et al. expands our understanding of miRNA biogenesis and maturation, elucidating a mechanism by which extracellular signaling directs cell differentiation via posttranscriptional regulation of miRNA expression.

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