Body-Interfaced Chemical Sensors for Noninvasive Monitoring and Analysis of Biofluids

Jie Zhao, Hexia Guo, Jinghua Li, Amay J. Bandodkar, John A. Rogers*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

69 Scopus citations


Body-interfaced sensors have received tremendous attention due to a broad and diverse collection of potential applications, from monitoring of health status to managing and preventing disease conditions. In this review article, we highlight the emerging sensing modalities and advanced materials/device designs in body-integrated flexible platforms capable of capturing and analyzing biofluids. In particular, we discuss different chemical sensors and biosensors for real-time noninvasive monitoring and analysis of metabolites and electrolytes in sweat, tears, saliva, and interstitial fluid. Finally, we show several techniques that could be integrated with body-interfaced sensors for data acquisition, signal processing, display, and communication.

Original languageEnglish (US)
Pages (from-to)559-571
Number of pages13
JournalTrends in Chemistry
Issue number6
StatePublished - Sep 2019


  • biochemical sensing mechanisms
  • biofluids
  • body-interfaced sensors
  • health monitoring
  • wireless systems

ASJC Scopus subject areas

  • General Chemistry


Dive into the research topics of 'Body-Interfaced Chemical Sensors for Noninvasive Monitoring and Analysis of Biofluids'. Together they form a unique fingerprint.

Cite this