Bolus shaping of contrast medium to adapt k-space sampling: adjusting injection protocol of magnetic resonance angiography for optimal images in a 3-T system

Biao Lu, Zhao Qi Zhang, Zhan Ming Fan, Kai Lin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To explore the possibility of shaping bolus of contrast medium to adapt k-space sampling to improve image quality in a 3-T system. Materials and Methods: Eighty patients suspected of having renal arterial disease or atherosclerosis were divided into four groups and underwent imaging with different high-spatial-resolution three-dimensional contrast-enhanced magnetic resonance angiography (MRA) scanning and injection protocol combinations. A group of 20 patients were injected single-dose contrast medium with a centric view ordering for k-space filling. Another group of 20 patients underwent MRA with double-dose and centric-view ordering. The bolus of contrast medium was shaped by adjusting injection protocol to adapt centric and sequential view ordering of sampling k-space, respectively, for other two groups. Then, the quality of image got with different protocols combination was compared, and the dose of contrast medium used in latter two groups was compared with single- and double-dose prescription basing on body weight. Result: Bolus shaped adapting to centric view ordering and sequential view ordering brings more homogeneous vessel signal. Individualized dose is lower than the double dose but higher than the single dose. Dose does not necessarily correlate with body weight. Conclusion: Under certain scanning protocol, appropriate shape of contrast medium passing through target vessel leads to higher-quality image and save contrast medium.

Original languageEnglish (US)
Pages (from-to)460-467
Number of pages8
JournalClinical Imaging
Volume32
Issue number6
DOIs
StatePublished - Nov 2008

Keywords

  • Contrast medium
  • Injection protocol
  • Magnetic resonance angiography
  • k-space sampling

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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