Bone changes from prostaglandin therapy

Andrew K Poznanski*, Sandra K. Fernbach, Teresa E. Berry

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Prostaglandin E therapy in infants causes periosteal elevation. Although the changes usually take 30-40 days to become visible, we have seen them as early as nine days. In 15 infants who had prostaglandin E therapy for over six days, three developed periosteal elevation. Three other cases are described in greater detail, with long-term follow-up in two in which the bone remodeled to normal. Gallium scan in one showed increased uptake in areas involved. The periosteal cloaking may mimic Caffey disease but the pattern of involvement is different, since the mandible, which is commonly affected in Caffey disease, is rarely involved in prostaglandin E therapy.

Original languageEnglish (US)
Pages (from-to)20-25
Number of pages6
JournalSkeletal Radiology
Volume14
Issue number1
DOIs
StatePublished - Jun 1 1985

Keywords

  • Periosteal elevation
  • Prostaglandin E

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging

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