TY - JOUR
T1 - Bone Marrow and Peripheral Blood Stem Cell Harvesting
AU - Treleaven, Jennifer G.
AU - Mehta, Jayesh
PY - 1992/1/1
Y1 - 1992/1/1
N2 - A number of malignant diseases are responsive to supralethal myelotoxic high-dose chemoradiotherapy, and can be treated with hematopoietic stem cell rescue. The number of genetic diseases correctable by replacement of defective pluripotent stem cells with normal stem cells or through gene transfer is ever-increasing. In all these cases, pluripotent hematopoietic stem cells need to be infused, which can be obtained directly from the bone marrow or from the peripheral blood with or without the aid of mobilizing strategies. This article is a detailed review of the technical and medical aspects of stem cell collection from the bone marrow and the peripheral blood.
AB - A number of malignant diseases are responsive to supralethal myelotoxic high-dose chemoradiotherapy, and can be treated with hematopoietic stem cell rescue. The number of genetic diseases correctable by replacement of defective pluripotent stem cells with normal stem cells or through gene transfer is ever-increasing. In all these cases, pluripotent hematopoietic stem cells need to be infused, which can be obtained directly from the bone marrow or from the peripheral blood with or without the aid of mobilizing strategies. This article is a detailed review of the technical and medical aspects of stem cell collection from the bone marrow and the peripheral blood.
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U2 - 10.1089/scd.1.1992.1.215
DO - 10.1089/scd.1.1992.1.215
M3 - Article
C2 - 1365028
AN - SCOPUS:0026928715
SN - 1061-6128
VL - 1
SP - 215
EP - 223
JO - Journal of Hematotherapy
JF - Journal of Hematotherapy
IS - 3
ER -