Bone mineral status in growth hormone deficiency

Richard M. Shore, Russell W. Chesney, Richard B. Mazess, Philip G. Rose, Gerald J. Bargman*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

91 Scopus citations


Bone mineral status was monitored by photon absorptiometry in 18 children with growth hormone deficiency. Before exogenous growth hormone therapy, bone mineral content, bone width, and BMC/BW were below predicted values. Delayed maturation, as assessed by skeletal age, accounted for approximately 35% of the deficit for these values. Height velocity doubled during therapy, and BMC, BW, and BMC/BW increased commensurate with height and weight increases so that the relative deficit was unchanged. The pathogenesis of relative osteopenia in growth hormone deficiency was not determined.

Original languageEnglish (US)
Pages (from-to)393-396
Number of pages4
JournalThe Journal of pediatrics
Issue number3 PART 1
StatePublished - Mar 1980

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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