Abstract
The establishment of new and effective approaches to regenerative medicine requires a high interdisciplinary character between materials science, biology and surgery; this new paradigm is today fostering large advances in materials science and a more clear definition of the key aspects related to bone tissue regeneration. In this respect new bio-inspired approaches for the synthesis of biomaterials, such as in vitro biomineralization, enables the production of a new generation of smart, multifunctional and stimuli-responsive biomimetic materials for hard tissue regeneration. Among these advances, the implementation of new functionalities triggered by external magnetic signals may open the way to new therapeutic approaches to increase the regenerative potential of the scaffold, also reducing invasiveness during the implantation surgery.
| Original language | English (US) |
|---|---|
| Title of host publication | Bone Substitute Biomaterials |
| Publisher | Elsevier Inc |
| Pages | 3-29 |
| Number of pages | 27 |
| ISBN (Electronic) | 9780857099037 |
| ISBN (Print) | 9780857094971 |
| DOIs | |
| State | Published - Jul 21 2014 |
Funding
The research leading to these results has received funding from the European Union’s Seventh Framework Programme ([FP7/2007–2013]) under grant agreement n° 246373, OPHIS.
Keywords
- Biomimesis
- Biomineralization
- Bone regeneration
- Magnetism
- Osteochondral regeneration
- Stimuli-responsive
ASJC Scopus subject areas
- General Engineering
- General Materials Science