Brain metastases in non-small-cell lung cancer: better outcomes through current therapies and utilization of molecularly targeted approaches

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

Non-small-cell lung cancer (NSCLC) patients experience a high incidence of brain metastases, de novo and recurrent. We review the mechanisms of brain metastases and promising NSCLC molecular markers to delineate potential future therapeutic targets. Discussed are the current and previously utilized roles of surgery, radiation (both therapeutic and prophylactic), and systemic therapies in the treatment of NSCLC brain metastases. Future directions for treatment of NSCLC brain metastases will conclude our review.

Original languageEnglish (US)
Pages (from-to)61-75
Number of pages15
JournalCNS oncology
Volume3
Issue number1
DOIs
StatePublished - Jan 1 2014

ASJC Scopus subject areas

  • Medicine(all)

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