Brain networks for analyzing eye gaze

Christine I. Hooker*, Ken A. Paller, Darren R. Gitelman, Todd B. Parrish, M. Marsel Mesulam, Paul J. Reber

*Corresponding author for this work

Research output: Contribution to journalArticle

155 Scopus citations

Abstract

The eyes convey a wealth of information in social interactions. This information is analyzed by multiple brain networks, which we identified using functional magnetic resonance imaging (MRI). Subjects attempted to detect a particular directional cue provided either by gaze changes on an image of a face or by an arrow presented alone or by an arrow superimposed on the face. Another control condition was included in which the eyes moved without providing meaningful directional information. Activation of the superior temporal sulcus accompanied extracting directional information from gaze relative to directional information from an arrow and relative to eye motion without relevant directional information. Such selectivity for gaze processing was not observed in face-responsive fusiform regions. Brain activations were also investigated while subjects viewed the same face but attempted to detect when the eyes gazed directly at them. Most notably, amygdala activation was greater during periods when direct gaze never occurred than during periods when direct gaze occurred on 40% of the trials. In summary, our results suggest that increases in neural processing in the amygdala facilitate the analysis of gaze cues when a person is actively monitoring for emotional gaze events, whereas increases in neural processing in the superior temporal sulcus support the analysis of gaze cues that provide socially meaningful spatial information.

Original languageEnglish (US)
Pages (from-to)406-418
Number of pages13
JournalCognitive Brain Research
Volume17
Issue number2
DOIs
StatePublished - Jul 15 2003

Keywords

  • Amygdala
  • Autism
  • Emotion
  • Face perception
  • Joint attention
  • Schizophrenia
  • Social cognition
  • Superior temporal sulcus (STS)
  • Theory of mind
  • fMRI

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

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