Brain Stimulation for Improving Sleep and Memory

Roneil G. Malkani*, Phyllis C. Zee

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

34 Scopus citations


Given the critical role of sleep, particularly sleep slow oscillations, sleep spindles, and hippocampal sharp wave ripples, in memory consolidation, sleep enhancement represents a key opportunity to improve cognitive performance. Techniques such as transcranial electrical and magnetic stimulation and acoustic stimulation can enhance slow oscillations and sleep spindles and potentially improve memory. Targeted memory reactivation in sleep may enhance or stabilize memory consolidation. Each technique has technical considerations that may limit its broader clinical application. Therefore, neurostimulation to enhance sleep quality, in particular sleep slow oscillations, has the potential for improving sleep-related memory consolidation in healthy and clinical populations.

Original languageEnglish (US)
Pages (from-to)101-115
Number of pages15
JournalSleep Medicine Clinics
Issue number1
StatePublished - Mar 2020


  • Acoustic stimulation
  • Brain stimulation
  • Closed-loop stimulation
  • Memory
  • Slow wave sleep
  • Targeted memory reactivation
  • Transcranial electric stimulation
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Clinical Psychology
  • Clinical Neurology
  • Psychiatry and Mental health


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