Brain Tumor Survival Prediction Using Radiomics Features

Sobia Yousaf, Syed Muhammad Anwar*, Harish RaviPrakash, Ulas Bagci

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Surgery planning in patients diagnosed with brain tumor is dependent on their survival prognosis. A poor prognosis might demand for a more aggressive treatment and therapy plan, while a favorable prognosis might enable a less risky surgery plan. Thus, accurate survival prognosis is an important step in treatment planning. Recently, deep learning approaches have been used extensively for brain tumor segmentation followed by the use of deep features for prognosis. However, radiomics-based studies have shown more promise using engineered/hand-crafted features. In this paper, we propose a three-step approach for multi-class survival prognosis. In the first stage, we extract image slices corresponding to tumor regions from multiple magnetic resonance image modalities. We then extract radiomic features from these 2D slices. Finally, we train machine learning classifiers to perform the classification. We evaluate our proposed approach on the publicly available BraTS 2019 data and achieve an accuracy of 76.5% and precision of 74.3% using the random forest classifier, which to the best of our knowledge are the highest reported results yet. Further, we identify the most important features that contribute in improving the prediction.

Original languageEnglish (US)
Title of host publicationMachine Learning in Clinical Neuroimaging and Radiogenomics in Neuro-oncology - 3rd International Workshop, MLCN 2020, and Second International Workshop, RNO-AI 2020, Held in Conjunction with MICCAI 2020, Proceedings
EditorsSeyed Mostafa Kia, Hassan Mohy-ud-Din, Ahmed Abdulkadir, Cher Bass, Mohamad Habes, Jane Maryam Rondina, Chantal Tax, Hongzhi Wang, Thomas Wolfers, Saima Rathore, Madhura Ingalhalikar
PublisherSpringer Science and Business Media Deutschland GmbH
Pages284-293
Number of pages10
ISBN (Print)9783030668426
DOIs
StatePublished - 2020
Event3rd International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2020, and 2nd International Workshop on Radiogenomics in Neuro-oncology, RNO-AI 2020, held in conjunction with MICCAI 2020 - Lima, Peru
Duration: Oct 4 2020Oct 8 2020

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume12449 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference3rd International Workshop on Machine Learning in Clinical Neuroimaging, MLCN 2020, and 2nd International Workshop on Radiogenomics in Neuro-oncology, RNO-AI 2020, held in conjunction with MICCAI 2020
CountryPeru
CityLima
Period10/4/2010/8/20

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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