TY - JOUR
T1 - Brainstem responses to speech syllables
AU - Russo, Nicole
AU - Nicol, Trent
AU - Musacchia, Gabriella
AU - Kraus, Nina
PY - 2004/9
Y1 - 2004/9
N2 - Objective: http://www.communication.northwestern.edu/csd/research/ brainvoltsTo establish reliable procedures and normative values to quantify brainstem encoding of speech sounds. Methods: Auditory brainstem responses to speech syllables presented in quiet and in background noise were obtained from 38 normal children. Brainstem responses consist of transient and sustained, periodic components - much like the speech signal itself. Transient peak responses were analyzed with measures of latency, amplitude, area, and slope. Magnitude of sustained, periodic frequency-following responses was assessed with root mean square, fundamental frequency, and first formant amplitudes; timing was assessed by stimulus-to-response and quiet-to-noise inter-response correlations. Results: Measures of transient and sustained components of the brainstem response to speech syllables were reliably obtained with high test-retest stability and low variability across subjects. All components of the brainstem response were robust in quiet. Background noise disrupted the transient responses whereas the sustained response was more resistant to the deleterious effects of noise. Conclusions: The speech-evoked brainstem response faithfully reflects many acoustic properties of the speech signal. Procedures to quantitatively describe it have been developed. Significance: Accurate and precise manifestation of stimulus timing at the auditory brainstem is a hallmark of the normal perceptual system. The brainstem response to speech sounds provides a mechanism for understanding the neural bases of normal and deficient attention-independent auditory function.
AB - Objective: http://www.communication.northwestern.edu/csd/research/ brainvoltsTo establish reliable procedures and normative values to quantify brainstem encoding of speech sounds. Methods: Auditory brainstem responses to speech syllables presented in quiet and in background noise were obtained from 38 normal children. Brainstem responses consist of transient and sustained, periodic components - much like the speech signal itself. Transient peak responses were analyzed with measures of latency, amplitude, area, and slope. Magnitude of sustained, periodic frequency-following responses was assessed with root mean square, fundamental frequency, and first formant amplitudes; timing was assessed by stimulus-to-response and quiet-to-noise inter-response correlations. Results: Measures of transient and sustained components of the brainstem response to speech syllables were reliably obtained with high test-retest stability and low variability across subjects. All components of the brainstem response were robust in quiet. Background noise disrupted the transient responses whereas the sustained response was more resistant to the deleterious effects of noise. Conclusions: The speech-evoked brainstem response faithfully reflects many acoustic properties of the speech signal. Procedures to quantitatively describe it have been developed. Significance: Accurate and precise manifestation of stimulus timing at the auditory brainstem is a hallmark of the normal perceptual system. The brainstem response to speech sounds provides a mechanism for understanding the neural bases of normal and deficient attention-independent auditory function.
KW - Auditory brainstem response
KW - Brainstem response
KW - Effects of noise
KW - Frequency-following response
KW - Speech syllable response
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U2 - 10.1016/j.clinph.2004.04.003
DO - 10.1016/j.clinph.2004.04.003
M3 - Article
C2 - 15294204
AN - SCOPUS:3843150496
VL - 115
SP - 2021
EP - 2030
JO - Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control
JF - Electroencephalography and Clinical Neurophysiology - Electromyography and Motor Control
SN - 1388-2457
IS - 9
ER -