Doença de lyme-símile Brasileira ou síndrome Baggio-Yoshinari: Zoonose exótica e emergente transmitida por carrapatos

Translated title of the contribution: Brazilian lyme-like disease or Baggio-Yoshinari syndrome: Exotic and emerging Brazilian tick-borne zoonosis

Natalino Hajime Yoshinari, Elenice Mantovani, Virgínia Lucia Nazario Bonoldi, Roberta Gonçalves Marangoni, Giancarla Gauditano

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations

Abstract

Lyme disease (LD) is a frequent zoonosis found in the Northern Hemisphere and is considered an infectious disease caused by spirochetes belonging sensu lato to the Borrelia burgdorferi complex transmitted by ticks of the Ixodes ricinus group. In 1992, first cases similar to LD were described in Brazil, when brothers, after a tick bite episode developed symptoms, as erythema migrans, general flu-like symptoms and arthritis. Careful analysis of Brazilian LD-like illness casuistry showed that epidemiological, clinical and laboratorial features in the country were very different from those exhibited by North American and Eurasian LD patients. Human blood-suckers Ixodes ricinus complex ticks were absent at risk areas; the disease is recurrent in the country; Borrelia burgdorferi was never isolated in Brazil and specific serologic tests have shown little positivity with inconsistent results. Furthermore, peripheral blood analysis of patients on electron microscopy exhibited structures resembling Mycoplasma spp, Chlamydia spp and spirochete-like microorganisms. In fact, they were assumed to be latent forms of spiro-chetes (L form or cell wall deficient bacteria) adapted to survive at inhospitable conditions in vertebrate and invertebrate hosts. For these reasons, the Brazilian zoonosis was named Baggio-Yoshinari Syndrome (BYS) and defined as: Exotic and emerging Brazilian infectious disease, transmitted by ticks not belonging to the Ixodes ricinus complex, caused by latent spirochetes with atypical morphology, which originates LD- like symptoms, except for occurrence of relapsing episodes and auto-immune disorders.

Translated title of the contributionBrazilian lyme-like disease or Baggio-Yoshinari syndrome: Exotic and emerging Brazilian tick-borne zoonosis
Original languagePortuguese
Pages (from-to)363-369
Number of pages7
JournalRevista da Associacao Medica Brasileira
Volume56
Issue number3
DOIs
StatePublished - 2010

Keywords

  • Borrelia burgdorferi
  • L forms
  • Lyme disease
  • Spirochaetales infections
  • Tick-borne diseases

ASJC Scopus subject areas

  • Medicine(all)

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