Breast cancer: Clinical Practice Guidelines in Oncology™

Robert W. Carlson, D. Craig Alfred, Benjamin O. Anderson, Harold J. Burstein, W. Bradford Carter, Stephen B. Edge, John K. Erban, William B. Farrar, Lori J. Goldstein, William J. Gradishar, Daniel F. Hayes, Clifford A. Hudis, Mohammad Jahanzeb, Krystyna Kiel, Britt Marie Ljung, P. Kelly Marcom, Ingrid A. Mayer, Beryl McCormick, Lisle M. Nabell, Lori J. PierceElizabeth C. Reed, Mary Lou Smith, George Somlo, Richard L. Theriault, Neal S. Topham, John H. Ward, Eric P. Winer, Antonio C. Wolff

Research output: Contribution to journalArticlepeer-review

391 Scopus citations


The therapeutic options for patients with noninvasive or invasive breast cancer are complex and varied. In many situations, the patient and physician have the responsibility to jointly explore and select the most appropriate option from among the available alternatives. With few exceptions, the evaluation, treatment, and follow-up recommendations in these guidelines are based on the results of past and present clinical trials. However, not a single clinical situation exists in which the treatment of breast cancer has been optimized with respect to either maximizing cure or minimizing toxicity and disfigurement. Therefore, patient/physician participation in prospective clinical trials allows patients to not only receive state-of-the-art cancer treatment but also contribute to improving the treatment of future patients.

Original languageEnglish (US)
Pages (from-to)122-192
Number of pages71
JournalJNCCN Journal of the National Comprehensive Cancer Network
Issue number2
StatePublished - Feb 2009


  • Adjuvant therapy
  • Breast cancer
  • Breast-conserving therapy
  • Chemotherapy
  • Ductal carcinoma in situ
  • Endocrine therapy
  • Lobular carcinoma in situ
  • Mastectomy
  • NCCN clinical practice guidelines
  • Radiation
  • Therapy

ASJC Scopus subject areas

  • Oncology


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