Breast Fibroadenoma with Increased Activity on 68Ga DOTATATE PET/CT

Georgios Z. Papadakis; Corina Millo; Samira M. Sadowski; Apostolos H. Karantanas; Ulas Bagci; Nicholas J. Patronas

doi:10.1097/RLU.0000000000001463

Breast Fibroadenoma with Increased Activity on ⁶⁸Ga DOTATATE PET/CT

Georgios Z. Papadakis^*, Corina Millo, Samira M. Sadowski, Apostolos H. Karantanas, Ulas Bagci, Nicholas J. Patronas

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Fibroadenoma is the most common benign breast tumor in women of reproductive age, carrying little to no risk of breast cancer development. We report on a case of a woman with history of neuroendocrine tumor who on follow-up imaging tests underwent whole-body PET/CT study using ⁶⁸Ga DOTATATE. The scan showed increased focal activity in the right breast, which was biopsied revealing a fibroadenoma. The presented data suggests cell surface overexpression of somatostatin receptors by this benign breast tumor. Moreover, this finding emphasizes the need for cautious interpretation of ⁶⁸Ga DOTATATE-avid breast lesions that could mimic malignancy in neuroendocrine tumor patients.

Original language	English (US)
Pages (from-to)	145-146
Number of pages	2
Journal	Clinical nuclear medicine
Volume	42
Issue number	2
DOIs	https://doi.org/10.1097/RLU.0000000000001463
State	Published - Feb 1 2017
Externally published	Yes

Keywords

Ga DOTATATE PET/CT
benign tumor
breast fibroadenoma
somatostatin receptors

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/RLU.0000000000001463

Cite this

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title = "Breast Fibroadenoma with Increased Activity on 68Ga DOTATATE PET/CT",

abstract = "Fibroadenoma is the most common benign breast tumor in women of reproductive age, carrying little to no risk of breast cancer development. We report on a case of a woman with history of neuroendocrine tumor who on follow-up imaging tests underwent whole-body PET/CT study using 68Ga DOTATATE. The scan showed increased focal activity in the right breast, which was biopsied revealing a fibroadenoma. The presented data suggests cell surface overexpression of somatostatin receptors by this benign breast tumor. Moreover, this finding emphasizes the need for cautious interpretation of 68Ga DOTATATE-avid breast lesions that could mimic malignancy in neuroendocrine tumor patients.",

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AU - Papadakis, Georgios Z.

AU - Millo, Corina

AU - Sadowski, Samira M.

AU - Karantanas, Apostolos H.

AU - Bagci, Ulas

AU - Patronas, Nicholas J.

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AB - Fibroadenoma is the most common benign breast tumor in women of reproductive age, carrying little to no risk of breast cancer development. We report on a case of a woman with history of neuroendocrine tumor who on follow-up imaging tests underwent whole-body PET/CT study using 68Ga DOTATATE. The scan showed increased focal activity in the right breast, which was biopsied revealing a fibroadenoma. The presented data suggests cell surface overexpression of somatostatin receptors by this benign breast tumor. Moreover, this finding emphasizes the need for cautious interpretation of 68Ga DOTATATE-avid breast lesions that could mimic malignancy in neuroendocrine tumor patients.

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