Buckled membranes in mixed-valence ionic amphiphile vesicles

Megan A. Greenfield, Liam C. Palmer, Graziano Vernizzi, Monica Olvera De La Cruz, Samuel I. Stupp

Research output: Contribution to journalArticlepeer-review

59 Scopus citations


(Figure Presented) Amphiphilic molecules can form closed-shell structures that are determined by competing attractive and repulsive forces. Since supramolecular shape has its roots in intermolecular interactions, the interplay of electrostatic, hydrophobic, and steric forces can generate nonspherical structures. Here we show that anionic and cationic amphiphiles of unequal charge can coassemble into small buckled vesicles and present a physical argument that explains this phenomenon. The strong electrostatic interaction between the +3 and -1 head groups increases the cohesion energy of the amphiphiles and favors the formation of twodimensional, flat ionic domains on the vesicle surface, resulting in edges and a buckled shape.

Original languageEnglish (US)
Pages (from-to)12030-12031
Number of pages2
JournalJournal of the American Chemical Society
Issue number34
StatePublished - Sep 2 2009

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry


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