Building an efficient factory: Where is pre-rRNA synthesized in the nucleolus?

Sui Huang*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

62 Scopus citations

Abstract

The subnucleolar structure that is involved in rDNA transcription has been controversial. A report by Koberna et al. (2002, this issue, page 743) adds significant weight toward the idea that dense fibrillar components (DFCs)* and fibrillar center (FC)/DFC borders are the sites of pre-rRNA synthesis.

Original languageEnglish (US)
Pages (from-to)739-741
Number of pages3
JournalJournal of Cell Biology
Volume157
Issue number5
DOIs
StatePublished - May 27 2002

Keywords

  • Br-U labeling
  • Christmas tree
  • Dense fibrillar components
  • Nucleolus
  • Sites of DNA transcription

ASJC Scopus subject areas

  • Cell Biology

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