Building biomechanical models based on medical image data: An assessment of model accuracy

Wendy M. Murray, Allison S. Arnold, Silvia Salinas, Mahidhar M. Durbhakula, Thomas S. Buchanan, Scott L. Delp

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Scopus citations

Abstract

The goals of this work were to (i) establish a method for building subject-specific biomechanical models from medical image data, (ii) construct a subject-specific model of the elbow, and (iii) quantify the accuracy of soft tissue excursions estimated from the model. We developed a kinematic model of the elbow joint and its surrounding musculature from magnetic resonance images of a 6'4” male cadaver specimen in one limb position. Moment arms estimated from the model (i. e., the changes in muscle-tendon lengths with elbow flexion angle) were compared to moment arms measured experimentally from the same specimen. In five of the six muscles studied, the model explained 84%-94% of the variation in the experimental data. Model estimates of peak elbow flexion moment arm were within 13% of the experimental peaks. Our results suggest that subject-specific musculoskeletal models derived from medical image data have the potential to substantially improve estimates of soft tissue excursions in living subjects.

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer-Assisted Intervention ─ MICCAI 1998 - 1st International Conference, Proceedings
EditorsWilliam M. Wells, Alan Colchester, Scott Delp
PublisherSpringer Verlag
Pages539-549
Number of pages11
ISBN (Print)3540651365, 9783540651369
DOIs
StatePublished - Jan 1 1998
Event1st International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 1998 - Cambridge, United States
Duration: Oct 11 1998Oct 13 1998

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume1496
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other1st International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 1998
CountryUnited States
CityCambridge
Period10/11/9810/13/98

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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    Murray, W. M., Arnold, A. S., Salinas, S., Durbhakula, M. M., Buchanan, T. S., & Delp, S. L. (1998). Building biomechanical models based on medical image data: An assessment of model accuracy. In W. M. Wells, A. Colchester, & S. Delp (Eds.), Medical Image Computing and Computer-Assisted Intervention ─ MICCAI 1998 - 1st International Conference, Proceedings (pp. 539-549). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 1496). Springer Verlag. https://doi.org/10.1007/bfb0056239