Burkitt translocation (8;22)(q24;q11) in a patient with multiple myeloma

Rogan Mon Look*, Stephen Wong Lim, Rhona Rebecca Schreck, Stephen Lee, Marie Perrelli Fuerst, Grace Natividad Lawrence, Donato Absalom Kusuanco, Christine Elisabeth Kessler, Francis Joseph Giles

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The prevalance of chromosomal abnormalities in multiple myeloma (MM) has been difficult to detect by karyotyping primarily because of the low proliferative rate of malignant plasma cells. The reported incidences of abnormal karyotypes range from 24% to 63% in bone marrows obtained from MM patients, with the higher rates being seen in aggressive disease [1-8]. Detection of abnormal karyotypes in MM has been associated with a poor prognosis. We report a MM patient with an 8;22 Burkitt translocation, the first such reported case.

Original languageEnglish (US)
Pages (from-to)100-102
Number of pages3
JournalCancer Genetics and Cytogenetics
Volume82
Issue number2
DOIs
StatePublished - Jul 15 1995

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Cancer Research

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