Bursting pressure of experimental aneurysms

M. R. Quigley; K. Heiferman; H. C. Kwaan; D. Vidovich; P. Nora; L. J. Cerullo

doi:10.3171/jns.1987.67.2.0288

Bursting pressure of experimental aneurysms

M. R. Quigley, K. Heiferman, H. C. Kwaan, D. Vidovich, P. Nora, L. J. Cerullo

Medicine, Hematology Oncology Division

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

The laser-sealed arteriotomy (LSA) technique was used to create experimental aneurysms in the rat carotid artery. Animals were reexplored 2, 4, and 8 weeks following LSA, at which time the aneurysms were measured and subjected to a bursting strength pressure. In addition, a group of hypertensive rats with LSA was also tested 2 weeks after surgery. The LSA procedure produced aneurysms of a stable size and bursting pressure over the time studied. The bursting pressure technique may be applicable for assessing aneurysm therapy in an experimental setting.

Original language	English (US)
Pages (from-to)	288-290
Number of pages	3
Journal	Journal of neurosurgery
Volume	67
Issue number	2
DOIs	https://doi.org/10.3171/jns.1987.67.2.0288
State	Published - 1987

ASJC Scopus subject areas

Surgery
Clinical Neurology

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10.3171/jns.1987.67.2.0288

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AU - Quigley, M. R.

AU - Heiferman, K.

AU - Kwaan, H. C.

AU - Vidovich, D.

AU - Nora, P.

AU - Cerullo, L. J.

PY - 1987

Y1 - 1987

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AB - The laser-sealed arteriotomy (LSA) technique was used to create experimental aneurysms in the rat carotid artery. Animals were reexplored 2, 4, and 8 weeks following LSA, at which time the aneurysms were measured and subjected to a bursting strength pressure. In addition, a group of hypertensive rats with LSA was also tested 2 weeks after surgery. The LSA procedure produced aneurysms of a stable size and bursting pressure over the time studied. The bursting pressure technique may be applicable for assessing aneurysm therapy in an experimental setting.

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Bursting pressure of experimental aneurysms

Abstract

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