C-18 Hydroxylation of gibberellins

Lewis N. Mander*, Regan J. Thomson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


A protocol for the hydroxylation of the 18-methyl group in gibberellins has been developed, as demonstrated by the successful synthesis of 18-hydroxy GA4 methyl ester by means of a tandem process involving the conjugate addition of alkoxide to the α-methylene lactone moiety of a ring A-seco-gibberellin followed by an intramolecular aldol reaction.

Original languageEnglish (US)
Pages (from-to)2893-2894
Number of pages2
JournalJournal of the Chemical Society, Perkin Transactions 1
Issue number17
StatePublished - Dec 1 2000

ASJC Scopus subject areas

  • Chemistry(all)


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