Caenorhabditis Elegans as a Model System to Study the Biology of Protein Aggregation and Toxicity

Elise A. Kikis*, Anat Ben-Zvi, Richard I Morimoto

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish (US)
Title of host publicationProtein Misfolding Diseases
Subtitle of host publicationCurrent and Emerging Principles and Therapies
PublisherJohn Wiley and Sons
Pages175-190
Number of pages16
ISBN (Print)9780471799283
DOIs
StatePublished - Jul 2 2010

Keywords

  • C. elegans models for neurodegenerative diseases of protein folding
  • Caenorhabditis elegans as a model system - in studying biology of protein aggregation and toxicity
  • RNAi screens, forward genetic screens performed - identifying modulators of polyQ protein aggregation/toxicity

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Kikis, E. A., Ben-Zvi, A., & Morimoto, R. I. (2010). Caenorhabditis Elegans as a Model System to Study the Biology of Protein Aggregation and Toxicity. In Protein Misfolding Diseases: Current and Emerging Principles and Therapies (pp. 175-190). John Wiley and Sons. https://doi.org/10.1002/9780470572702.ch9