Calcaneal quantitative ultrasound compared with hip and femoral neck dual-energy x-ray absorptiometry in people with a spinal cord injury

Thomas J Schnitzer*, Nicole M Wysocki, Danielle Barkema, James W Griffith, Victoria Lent, Meghan Romba, Rachel Welbel, Sheena Bhuva, Bindu Manyam, Sarah K Linn

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Objective: To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population. Design: Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability. Setting: Inpatients and outpatients at a single acute rehabilitation hospital. Participants: A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury. Methods: Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA. Main Outcome Measurements: Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores. Results: Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI. Conclusions: A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.

Original languageEnglish (US)
Pages (from-to)748-755
Number of pages8
JournalPM and R
Volume4
Issue number10
DOIs
StatePublished - Oct 1 2012

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Neurology
  • Clinical Neurology

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