Calcaneal quantitative ultrasound compared with hip and femoral neck dual-energy x-ray absorptiometry in people with a spinal cord injury

Thomas J Schnitzer*, Nicole M Wysocki, Danielle Barkema, James W Griffith, Victoria Lent, Meghan Romba, Rachel Welbel, Sheena Bhuva, Bindu Manyam, Sarah K Linn

*Corresponding author for this work

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective: To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population. Design: Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability. Setting: Inpatients and outpatients at a single acute rehabilitation hospital. Participants: A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury. Methods: Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA. Main Outcome Measurements: Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores. Results: Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI. Conclusions: A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.

Original languageEnglish (US)
Pages (from-to)748-755
Number of pages8
JournalPM and R
Volume4
Issue number10
DOIs
StatePublished - Oct 1 2012

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Femur Neck
Spinal Cord Injuries
Hip
X-Rays
Bone Density
Osteoporosis
Inpatients
Outpatients
Bone and Bones
Wounds and Injuries
Disabled Persons
ROC Curve
Area Under Curve
Registries
Spine
Rehabilitation
Sensitivity and Specificity
Health
Population

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Neurology
  • Clinical Neurology

Cite this

Schnitzer, Thomas J ; Wysocki, Nicole M ; Barkema, Danielle ; Griffith, James W ; Lent, Victoria ; Romba, Meghan ; Welbel, Rachel ; Bhuva, Sheena ; Manyam, Bindu ; Linn, Sarah K. / Calcaneal quantitative ultrasound compared with hip and femoral neck dual-energy x-ray absorptiometry in people with a spinal cord injury. In: PM and R. 2012 ; Vol. 4, No. 10. pp. 748-755.
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Calcaneal quantitative ultrasound compared with hip and femoral neck dual-energy x-ray absorptiometry in people with a spinal cord injury. / Schnitzer, Thomas J; Wysocki, Nicole M; Barkema, Danielle; Griffith, James W; Lent, Victoria; Romba, Meghan; Welbel, Rachel; Bhuva, Sheena; Manyam, Bindu; Linn, Sarah K.

In: PM and R, Vol. 4, No. 10, 01.10.2012, p. 748-755.

Research output: Contribution to journalArticle

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T1 - Calcaneal quantitative ultrasound compared with hip and femoral neck dual-energy x-ray absorptiometry in people with a spinal cord injury

AU - Schnitzer, Thomas J

AU - Wysocki, Nicole M

AU - Barkema, Danielle

AU - Griffith, James W

AU - Lent, Victoria

AU - Romba, Meghan

AU - Welbel, Rachel

AU - Bhuva, Sheena

AU - Manyam, Bindu

AU - Linn, Sarah K

PY - 2012/10/1

Y1 - 2012/10/1

N2 - Objective: To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population. Design: Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability. Setting: Inpatients and outpatients at a single acute rehabilitation hospital. Participants: A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury. Methods: Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA. Main Outcome Measurements: Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores. Results: Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI. Conclusions: A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.

AB - Objective: To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population. Design: Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability. Setting: Inpatients and outpatients at a single acute rehabilitation hospital. Participants: A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury. Methods: Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA. Main Outcome Measurements: Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores. Results: Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI. Conclusions: A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.

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