Abstract
Objective: To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population. Design: Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability. Setting: Inpatients and outpatients at a single acute rehabilitation hospital. Participants: A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury. Methods: Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA. Main Outcome Measurements: Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores. Results: Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI. Conclusions: A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 748-755 |
| Number of pages | 8 |
| Journal | PM and R |
| Volume | 4 |
| Issue number | 10 |
| DOIs | |
| State | Published - Oct 1 2012 |
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ASJC Scopus subject areas
- Physical Therapy, Sports Therapy and Rehabilitation
- Rehabilitation
- Neurology
- Clinical Neurology
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Calcaneal quantitative ultrasound compared with hip and femoral neck dual-energy x-ray absorptiometry in people with a spinal cord injury. / Schnitzer, Thomas J; Wysocki, Nicole M; Barkema, Danielle; Griffith, James W; Lent, Victoria; Romba, Meghan; Welbel, Rachel; Bhuva, Sheena; Manyam, Bindu; Linn, Sarah K.
In: PM and R, Vol. 4, No. 10, 01.10.2012, p. 748-755.Research output: Contribution to journal › Article
TY - JOUR
T1 - Calcaneal quantitative ultrasound compared with hip and femoral neck dual-energy x-ray absorptiometry in people with a spinal cord injury
AU - Schnitzer, Thomas J
AU - Wysocki, Nicole M
AU - Barkema, Danielle
AU - Griffith, James W
AU - Lent, Victoria
AU - Romba, Meghan
AU - Welbel, Rachel
AU - Bhuva, Sheena
AU - Manyam, Bindu
AU - Linn, Sarah K
PY - 2012/10/1
Y1 - 2012/10/1
N2 - Objective: To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population. Design: Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability. Setting: Inpatients and outpatients at a single acute rehabilitation hospital. Participants: A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury. Methods: Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA. Main Outcome Measurements: Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores. Results: Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI. Conclusions: A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.
AB - Objective: To evaluate the sensitivity and specificity of calcaneal quantitative ultrasound (QUS) measurements for identifying osteoporosis determined by dual-energy x-ray absorptiometry (DXA) at the hip in a spinal cord injury (SCI) population. Design: Cross-sectional retrospective review of data collected in the bone health registry of persons with a disability. Setting: Inpatients and outpatients at a single acute rehabilitation hospital. Participants: A convenience sample of 66 participants, both inpatients and outpatients, with a spinal cord injury. Methods: Calcaneal T scores were determined by ultrasound, and bone density of the lumbar spine, total hip, and femoral neck were determined by DXA. Main Outcome Measurements: Right and left calcaneal QUS T scores and right and left hip and femoral neck DXA T scores. Results: Right and left hip DXA T scores were strongly associated with corresponding right and left calcaneal QUS T scores (right: r = .72, P < .001; left: r = .70, P < .001). Similar associations were found when we evaluated femoral neck T scores and calcaneal QUS T scores. Receiver operating characteristic analysis for evaluating QUS to identify DXA-defined osteoporosis demonstrated an area under the curve of 0.81 for all participants (acute and chronic injury) and 0.68 for those with a chronic SCI. Conclusions: A strong association exists between calcaneal QUS T scores and bone density T scores at the hip measured by DXA. QUS may have a place in the screening of people with SCI 1 year or more after their injury to evaluate their bone status.
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UR - http://www.scopus.com/inward/citedby.url?scp=84867894991&partnerID=8YFLogxK
U2 - 10.1016/j.pmrj.2012.05.011
DO - 10.1016/j.pmrj.2012.05.011
M3 - Article
VL - 4
SP - 748
EP - 755
JO - PM and R
JF - PM and R
SN - 1934-1482
IS - 10
ER -