Calcifying fibrous pseudotumor involving the neck of a five-week-old infant. Presence of factor XIIIa in the lesional cells

Kalisha A. Hill, Frank Gonzalez-Crussi, Attila Omeroglu, Pauline M. Chou*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

Calcifying fibrous pseudotumor is an uncommon lesion characterized by hyalinized collagen, psammomatous or dystrophic calcifications, and a predominantly lymphoplasmacytic infiltrate. Although the pathogenesis is unclear, a possible relationship with other inflammatory 'pseudotumors' has been proposed. We describe the pathology of two right neck calcifying fibrous pseudotumors present in a five-week-old female infant. The masses had many of the pathologic features of calcifying fibrous pseudotumor. The presence of a florid, mixed infiltrate, and the occurrence of more than one lesion in the same patient, favor the proposal that calcifying fibrous pseudotumor may be a sclerosing end stage of inflammatory myofibroblastic tumor. However, the presence of a previously undescribed participation of Factor XIIIa - positive cells suggests that the tumor may be of dermal dendrocyte origin.

Original languageEnglish (US)
Pages (from-to)527-531
Number of pages5
JournalPathology Research and Practice
Volume196
Issue number7
DOIs
StatePublished - 2000

Keywords

  • Calcifying fibrous pseudotumor
  • Factor XIIIa
  • Inflammatory myofibroblastic tumor
  • Neck

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Cell Biology

Fingerprint Dive into the research topics of 'Calcifying fibrous pseudotumor involving the neck of a five-week-old infant. Presence of factor XIIIa in the lesional cells'. Together they form a unique fingerprint.

Cite this