@article{d8cd7806f3a242559e57013931bcb94e,
title = "Caloric restriction lowers blood pressure in the spontaneously hypertensive rat",
abstract = "In the spontaneously hypertensive rat (SHR), caloric restriction without sodium restriction is associated with reduced blood pressure. Four days of fasting lowered blood pressure 19% while 4 days of eating 50% of ad lib intake reduced blood pressure 10%. Similar dietary changes had less effect on blood pressure in normotensive rats of the same strain (Wistar-Kyoto-WKY). These data are consistent with the hypothesis that caloric restriction lowers sympathetic activity.",
author = "Young, {James B.} and Deborah Mullen and Lewis Landsberg",
note = "Funding Information: From the Thorndike Laboratory and the Department of Medicine, Harvard Medical School and Beth Israel Hospital, Boston, Mass. Receivedforpublication March 16, 1978. Supported in part by USPHS Grants AM-20378 and RR-76. Dr. Young is the recipient of USPHS Fellowship AM-05755. Address reprint requests to Dr. James B. Young, Department of Medicine, Beth Israel Hospital, 330 Brookline Avenue, Boston, Mass. 02215. 0 1978 by Grune & Stratton, Inc., 0026-0495/78/27/2-0001$01.00/0",
year = "1978",
month = dec,
doi = "10.1016/0026-0495(78)90256-1",
language = "English (US)",
volume = "27",
pages = "1711--1714",
journal = "Metabolism: Clinical and Experimental",
issn = "0026-0495",
publisher = "W.B. Saunders Ltd",
number = "12",
}
