Abstract
In the spontaneously hypertensive rat (SHR), caloric restriction without sodium restriction is associated with reduced blood pressure. Four days of fasting lowered blood pressure 19% while 4 days of eating 50% of ad lib intake reduced blood pressure 10%. Similar dietary changes had less effect on blood pressure in normotensive rats of the same strain (Wistar-Kyoto-WKY). These data are consistent with the hypothesis that caloric restriction lowers sympathetic activity.
Original language | English (US) |
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Pages (from-to) | 1711-1714 |
Number of pages | 4 |
Journal | Metabolism |
Volume | 27 |
Issue number | 12 |
DOIs | |
State | Published - Dec 1978 |
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Endocrinology