Calvarial and skull base metastases: Comparison of nonenhanced and Gd-DTPA-enhanced MR images

Michele S. West, Eric J. Russell*, Robert Breit, Gordon Sze, Kwang S. Kim

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

33 Scopus citations


Fourteen patients with calvarial metastases were studied with magnetic resonance (MR) imaging before and after intravenous administration of gadolinium diethylenetriaminepentaacetic acid (DTPA) to evaluate the utility of contrast material enhancement for the detection of calvarial metastatic tumor. MR imaging was also performed before and after enhancement in 60 patients for reasons other than evaluation of metastases or calvarial tumor, to determine the appearance of the normal calvaria with enhancement. The normal pattern of fat distribution in the diploic space was typically symmetric. Except for enhancement of diploic veins and meninges near pacchionian granulations, the normal diploic space did not enhance. Calvarial metastases typically enhanced with Gd-DTPA. Enhanced MR images were superior to nonenhanced studies for detecting subtle intradiploic metastases but were inferior to nonenhanced studies for detecting tumor extension into fat-containing areas. Careful comparison of nonenhanced and enhanced MR images is required for complete evaluation of lesions affecting the calvaria and skull base.

Original languageEnglish (US)
Pages (from-to)85-91
Number of pages7
Issue number1
StatePublished - Jan 1990


  • Gadolinium
  • Magnetic resonance (MR), contrast enhancement, 11.1214, 12.1214
  • Skull, MR studies, 11.1214, 12.1214
  • Skull, anatomy, 11.92, 12.92
  • Skull, secondary neoplasms, 11.33, 12.33

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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