TY - JOUR
T1 - Cancer and pregnancy
AU - Williams, S. F.
AU - Bitran, J. D.
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 1985
Y1 - 1985
N2 - The most common malignancies occurring in women of child-bearing ages include breast, cervical, genital, and GI malignancies, and melanoma, lymphoma, and leukemia. Pregnancy does not appear to adversely affect the outcome of most tumors but may affect those that are known to be hormonally dependent. The approach in general to malignancy during pregnancy needs to be individualized. Therapy, whether by radiation or with cytotoxic drugs, has the greatest potential for fetal risk during the first trimester but more acceptable risk in the second and third trimesters. There are many unanswered questions concerning long-term effects of malignancy and its therapy upon the surviving child.
AB - The most common malignancies occurring in women of child-bearing ages include breast, cervical, genital, and GI malignancies, and melanoma, lymphoma, and leukemia. Pregnancy does not appear to adversely affect the outcome of most tumors but may affect those that are known to be hormonally dependent. The approach in general to malignancy during pregnancy needs to be individualized. Therapy, whether by radiation or with cytotoxic drugs, has the greatest potential for fetal risk during the first trimester but more acceptable risk in the second and third trimesters. There are many unanswered questions concerning long-term effects of malignancy and its therapy upon the surviving child.
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U2 - 10.1016/s0095-5108(18)30859-5
DO - 10.1016/s0095-5108(18)30859-5
M3 - Review article
C2 - 3902315
AN - SCOPUS:0022341428
SN - 0095-5108
VL - 12
SP - 609
EP - 623
JO - Clinics in Perinatology
JF - Clinics in Perinatology
IS - 3
ER -
