Cancer cells tune the signaling pathways to empower de novo synthesis of nucleotides

Keyphrases

• Signaling Pathway 100%
• Cancer Cells 100%
• Nucleotide Synthesis 100%
• Oncogene 60%
• Tumor Suppressor 60%
• Molecular Mechanism 40%
• Tumor Cells 20%
• Macromolecules 20%
• In Cancer 20%
• Homeostasis 20%
• Metabolism 20%
• Metabolic Pathway 20%
• Molecular Determinants 20%
• Energy Conservation 20%
• Cell Growth 20%
• MTOR Pathway 20%
• Liver Kinase B1 (LKB1) 20%
• Hyperactivity 20%
• Protein Synthesis 20%
• Tumor Protein p53 (TP53) 20%
• Metabolic Requirements 20%
• Signaling Activity 20%
• Glycosylation 20%
• Cancer Cell Proliferation 20%
• Signaling Hub 20%
• Nucleic Acid Synthesis 20%
• Nucleotide Pool 20%
• Metabolic Landscape 20%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Nucleotide Metabolism 83%
• Oncogene 50%
• Tumor Suppressor Protein 50%
• Metabolic Pathway 33%
• Glycosylation 16%
• Macromolecule 16%
• Mammalian Target of Rapamycin 16%
• Nucleic Acid Synthesis 16%
• Protein Biosynthesis 16%
• Homeostasis 16%
• Cell Proliferation 16%
• Cell Growth 16%
• Protein Kinase B 16%