Cap polyposis with protein-losing enteropathy

Marlene Gallegos*, Cynthia Lau, Dawn P. Bradly, Luis Blanco, Ali Keshavarzian, Shriram M. Jakate

*Corresponding author for this work

Research output: Contribution to journalArticle

5 Scopus citations


This case study is the ninth case reported since the last large series in 2003. Before establishing the diagnosis of cap polyposis, 4 of the 9 patients were initially diagnosed with ulcerative colitis and 1 patient was diagnosed with mucosal prolapse syndrome. Upon treatment, 4 of the 9 patients were treated for H. pylori infection, which resulted in the eradication of their gastritis and polyps. Resolution of cap polyposis was experienced after infliximab (Remicade, Centocor) in 1 patient, polypectomy in another patient, and total colectomy in a third patient; a fourth patient experienced complete resolution without any treatment. Many researchers attribute cap polyposis to mucosal prolapse syndrome; however, the exact mechanism of the underlying cause and the appropriate treatment strategy have not yet been elucidated.

Original languageEnglish (US)
Pages (from-to)415-420
Number of pages6
JournalGastroenterology and Hepatology
Issue number6
StatePublished - Jun 1 2011


ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

Cite this

Gallegos, M., Lau, C., Bradly, D. P., Blanco, L., Keshavarzian, A., & Jakate, S. M. (2011). Cap polyposis with protein-losing enteropathy. Gastroenterology and Hepatology, 7(6), 415-420.