Capsule Studies Performed in a Tertiary Care Center Versus Community Referrals Prior to Single-Balloon Enteroscopy: Does It Matter?

Andrea C. Rodriguez*, Ashok Shiani, Seth Lipka, Kirbylee K. Nelson, Ashley H. Davis-Yadley, Roshanak Rabbanifard, Ambuj Kumar, Patrick G. Brady

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


Background and Aims: Within the community, patients with positive capsule endoscopy (CE) are often referred to centers performing balloon-assisted enteroscopy. There is limited data evaluating the concordance and diagnostic/therapeutic yield of CE performed in the community versus CE conducted at institutions experienced with enteroscopy. The primary aim of this retrospective study was to evaluate the concordance between CE and SBE after CE was performed either in the community or at our tertiary care center. Methods: A total of 141 patients were analyzed after selecting patients undergoing evaluation of obscure GI bleeding from January 2010 to May 2014. Forty-seven CE were performed inside and the remaining 94 CE were performed at outside institutions prior to single-balloon enteroscopy at our institution. Agreement beyond chance was evaluated using kappa coefficient. A p value <5 % was considered significant. Results: The most frequent findings on CE were vascular lesions in 39 patients (41.5 %) within the referral group and 23 within inside patients (48.9 %), followed by active bleeding/clots in 23 patients (24.5 %) and in 14 patients (29.8 %) respectively. There was a fair degree of concordance in the referral group for vascular lesions 0.23 (0.03–0.42) compared to a good degree in the inside group 0.65 (0.44–0.87). Fair agreement was found looking at ulcers within the referral group 0.29 (0.06–0.65) compared to a moderate agreement in the inside group 0.55 (0.17–0.94). Conclusions: Degree of concordance for vascular lesions and ulcers was significantly higher for patients undergoing CE at our institution compared to those referred from the community. Patients referred to tertiary care centers for balloon-assisted enteroscopy may benefit from advanced endoscopists re-reading the capsule findings or even potentially repeating CE in hemodynamically stable patients if the study is not available.

Original languageEnglish (US)
Pages (from-to)3716-3720
Number of pages5
JournalDigestive diseases and sciences
Issue number12
StatePublished - Dec 1 2015
Externally publishedYes


  • Balloon-assisted enteroscopy
  • Capsule endoscopy
  • Concordance
  • Obscure
  • Obscure gastrointestinal bleeding
  • Occult
  • Single-balloon enteroscopy

ASJC Scopus subject areas

  • Gastroenterology
  • Physiology


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