Carbapenem-resistant Acinetobacter baumannii infections after organ transplantation: Short communication

P. Reddy*, T. R. Zembower, M. G. Ison, T. A. Baker, V. Stosor

*Corresponding author for this work

Research output: Contribution to journalArticle

41 Scopus citations

Abstract

Multi-drug resistant (MDR) gram-negative infections among solid organ transplant (SOT) recipients have long been associated with high morbidity and mortality. Acinetobacter baumannii has emerged as a potent nosocomial pathogen with the recent acquisition of resistance to broad-spectrum β-lactams, aminoglycosides, fluoroquinolones, and most notably, carbapenems. Despite a national rise in carbapenem-resistant A. baumannii (CRAB) infections, outcomes among SOT recipients with this emerging MDR pathogen are largely unknown. This single-center cohort is the first to describe the characteristics, complications, and outcomes among abdominal organ transplant recipients with CRAB. The current study suggests that SOT patients with CRAB suffer from prolonged hospitalization, infection with other MDR organisms, allograft dysfunction and loss, and high overall infection-related mortality.

Original languageEnglish (US)
Pages (from-to)87-93
Number of pages7
JournalTransplant Infectious Disease
Volume12
Issue number1
DOIs
StatePublished - Feb 1 2010

Keywords

  • Acinetobacter
  • Complications
  • Infections
  • Organ transplantation

ASJC Scopus subject areas

  • Transplantation
  • Infectious Diseases

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