CardiacNET: Segmentation of left atrium and proximal pulmonary veins from MRI using multi-view CNN

Aliasghar Mortazi*, Rashed Karim, Kawal Rhode, Jeremy Burt, Ulas Bagci

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

46 Scopus citations

Abstract

Anatomical and biophysical modeling of left atrium (LA) and proximal pulmonary veins (PPVs) is important for clinical management of several cardiac diseases. Magnetic resonance imaging (MRI) allows qualitative assessment of LA and PPVs through visualization. However, there is a strong need for an advanced image segmentation method to be applied to cardiac MRI for quantitative analysis of LA and PPVs. In this study, we address this unmet clinical need by exploring a new deep learning-based segmentation strategy for quantification of LA and PPVs with high accuracy and heightened efficiency. Our approach is based on a multi-view convolutional neural network (CNN) with an adaptive fusion strategy and a new loss function that allows fast and more accurate convergence of the backpropagation based optimization. After training our network from scratch by using more than 60K 2D MRI images (slices), we have evaluated our segmentation strategy to the STACOM 2013 cardiac segmentation challenge benchmark. Qualitative and quantitative evaluations, obtained from the segmentation challenge, indicate that the proposed method achieved the state-of-the-art sensitivity (90%), specificity (99%), precision (94%), and efficiency levels (10s in GPU, and 7.5 min in CPU).

Original languageEnglish (US)
Title of host publicationMedical Image Computing and Computer Assisted Intervention − MICCAI 2017 - 20th International Conference, Proceedings
EditorsPierre Jannin, Simon Duchesne, Maxime Descoteaux, Alfred Franz, D. Louis Collins, Lena Maier-Hein
PublisherSpringer Verlag
Pages377-385
Number of pages9
ISBN (Print)9783319661841
DOIs
StatePublished - 2017
Externally publishedYes
Event20th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017 - Quebec City, Canada
Duration: Sep 11 2017Sep 13 2017

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume10434 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference20th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017
CountryCanada
CityQuebec City
Period9/11/179/13/17

Keywords

  • Cardiac magnetic resonance
  • CardiacNET
  • Deep learning
  • Image segmentation
  • Left atrium
  • MRI
  • Pulmonary veins

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

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