Cardioembolic stroke

Issam Mikati, Zeina Ibrahim

Research output: Chapter in Book/Report/Conference proceedingChapter


Cardioembolic strokes account for 15-40 percent of all ischemic strokes, and cryptogenic strokes account for an even higher 30-40 percent of the remaining cerebral infarctions. Transthoracic echocardiography (TTE) is recommended if there is clinical suspicion of a cardiac mass, endocarditis or for re-evaluation of high-risk individuals with risk of progression or complication with infective endocarditis. Currently, computed tomography angiography (CTA) is mainly used to evaluate the thoracic aorta for atherosclerotic plaque in extent of burden of the disease. The most prevalent source of a cardioembolic stroke is a thrombus located within the left atrial appendage (LAA). Myxomas, the most common primary cardiac tumors, are mostly located in the left atrium. Papillary fibroelastomas (PFE) are the second most common primary cardiac tumor in adults. Various valvular disorders, affecting both native and prosthetic cardiac valves, can lead to the development of systemic and pulmonary embolus.

Original languageEnglish (US)
Title of host publicationWarlow’s Stroke
Subtitle of host publicationPractical Management
Number of pages25
ISBN (Electronic)9781118492390
ISBN (Print)9781118492222
StatePublished - Jan 1 2019


  • Atherosclerotic plaque
  • Cardiac tumors
  • Cardioembolic strokes
  • Computed tomography angiography
  • Left atrial appendage
  • Myxomas
  • Papillary fibroelastomas
  • Transthoracic echocardiography
  • Valvular disorders

ASJC Scopus subject areas

  • Medicine(all)


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