Abstract
The circadian system involves a 24 hr pacemaker that organizes daily rhythms and synchronizes physiological functions. Circadian misalignment can occur between internal clocks and external influences (e.g., light-dark cycle, food intake) or internally between the central and peripheral clocks. Misalignment is common in shift workers and those with abnormal meal and/or sleep timing. Experimental and observational studies have linked circadian misalignment to adverse cardiometabolic health including elevated glucose levels, elevated blood pressure, dyslipidemia and cardiovascular disease. This article discusses recent findings, including emerging interventions to reduce cardiometabolic consequences of circadian misalignment such as light therapy, melatonin, sleep and meal timing interventions.
Original language | English (US) |
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Title of host publication | Encyclopedia of Sleep and Circadian Rhythms |
Subtitle of host publication | Volume 1-6, Second Edition |
Publisher | Elsevier |
Pages | 644-656 |
Number of pages | 13 |
ISBN (Electronic) | 9780323910941 |
DOIs | |
State | Published - Jan 1 2023 |
Keywords
- Blood pressure
- Cardiovascular
- Chronotype
- Circadian disruption
- Diabetes
- Glucose
- Hypertension
- Insulin
- Light at night
- Meal timing
- Melatonin
- Shift work
- Sleep
- Sleep variability
ASJC Scopus subject areas
- General Neuroscience