Cardiovascular health metrics among South Asian adults in the United States

Prevalence and associations with subclinical atherosclerosis

Sameera A. Talegawkar, Yichen Jin, Namratha R Kandula, Alka M. Kanaya

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

South Asians, a fast growing ethnic group in the US, have an increased risk for cardiovascular disease compared to the general population. We examined the prevalence and distribution of the American Heart Association's Life's Simple 7 cardiovascular health (CVH) metrics using data from Mediators of Atherosclerosis in South Asians Living in America (MASALA) study, and cross-sectional associations between number of CVH metrics in the ideal range with subclinical atherosclerosis assessed using coronary artery calcium (CAC) measured using cardiac computed tomography and carotid intima media thickness (CIMT) measured using high-resolution B-mode ultrasonography. CAC was modeled as Agatston scores = 0, 1–400 and > 400; CIMT was examined continuously and as internal CIMT > 1.5 mm. In the MASALA cohort (N = 875; mean age: 55 years; 53% men; living in greater San Francisco and Chicago areas; October 2010–March 2013) without prevalent coronary heart disease, no participant had all 7 metrics in ideal range; approximately 20% of the participants had at least 5 metrics in ideal range. Higher number of CVH metrics in the ideal range was inversely associated with subclinical atherosclerosis. A 1 unit increase in the number of CVH metrics in the ideal range was associated with 32% lower odds of CAC = 1–400 (vs. CAC = 0; OR = 0.68, 95% CI: 0.60, 0.78) and 28% lower odds of internal CIMT > 1.5 mm (OR = 72, 95% CI: 0.61, 0.85). These data show the prevalence of CVH metrics among South Asians in the US, and provide empirical evidence on inverse associations of meeting ideal levels for higher number of metrics and subclinical atherosclerosis.

Original languageEnglish (US)
Pages (from-to)79-84
Number of pages6
JournalPreventive Medicine
Volume96
DOIs
StatePublished - Mar 1 2017

Fingerprint

Carotid Intima-Media Thickness
Atherosclerosis
Coronary Vessels
Health
Calcium
American Heart Association
San Francisco
Ethnic Groups
Coronary Disease
Ultrasonography
Cardiovascular Diseases
Cross-Sectional Studies
Tomography
Population

Keywords

  • Cardiovascular health metrics
  • Prevention
  • South Asians
  • Sub-clinical atherosclerosis

ASJC Scopus subject areas

  • Epidemiology
  • Public Health, Environmental and Occupational Health

Cite this

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title = "Cardiovascular health metrics among South Asian adults in the United States: Prevalence and associations with subclinical atherosclerosis",
abstract = "South Asians, a fast growing ethnic group in the US, have an increased risk for cardiovascular disease compared to the general population. We examined the prevalence and distribution of the American Heart Association's Life's Simple 7 cardiovascular health (CVH) metrics using data from Mediators of Atherosclerosis in South Asians Living in America (MASALA) study, and cross-sectional associations between number of CVH metrics in the ideal range with subclinical atherosclerosis assessed using coronary artery calcium (CAC) measured using cardiac computed tomography and carotid intima media thickness (CIMT) measured using high-resolution B-mode ultrasonography. CAC was modeled as Agatston scores = 0, 1–400 and > 400; CIMT was examined continuously and as internal CIMT > 1.5 mm. In the MASALA cohort (N = 875; mean age: 55 years; 53{\%} men; living in greater San Francisco and Chicago areas; October 2010–March 2013) without prevalent coronary heart disease, no participant had all 7 metrics in ideal range; approximately 20{\%} of the participants had at least 5 metrics in ideal range. Higher number of CVH metrics in the ideal range was inversely associated with subclinical atherosclerosis. A 1 unit increase in the number of CVH metrics in the ideal range was associated with 32{\%} lower odds of CAC = 1–400 (vs. CAC = 0; OR = 0.68, 95{\%} CI: 0.60, 0.78) and 28{\%} lower odds of internal CIMT > 1.5 mm (OR = 72, 95{\%} CI: 0.61, 0.85). These data show the prevalence of CVH metrics among South Asians in the US, and provide empirical evidence on inverse associations of meeting ideal levels for higher number of metrics and subclinical atherosclerosis.",
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Cardiovascular health metrics among South Asian adults in the United States : Prevalence and associations with subclinical atherosclerosis. / Talegawkar, Sameera A.; Jin, Yichen; Kandula, Namratha R; Kanaya, Alka M.

In: Preventive Medicine, Vol. 96, 01.03.2017, p. 79-84.

Research output: Contribution to journalArticle

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T1 - Cardiovascular health metrics among South Asian adults in the United States

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AU - Talegawkar, Sameera A.

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