Carotid intima-media thickness and distensibility measured by MRI at 3 T versus high-resolution ultrasound

Andreas Harloff*, Timo Zech, Alex Frydrychowicz, Martin Schumacher, Joachim Schölhorn, Jürgen Hennig, Cornelius Weiller, Michael Markl

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

We evaluated an MRI protocol at 3 T for the assessment of morphological and functional properties of the common carotid artery (CCA) in 32 healthy volunteers and 20 patients with high-grade internal carotid artery stenosis. Wall thickness of the CCA was measured by using multislice 2D T2 dark blood fast spin echo sequences and compared with intima-media thickness (IMT) determined by ultrasound. Carotid distensibility coefficient (DC) quantified by blood pressure and CCA diameter change during the cardiac cycle was measured by ECG gated 3D T1 CINE MRI and M-mode ultrasound. Apart from generally higher values in MRI high agreement was found for wall thickness and compliance in volunteers and patients. Remaining differences between both methods may be attributed to slightly different methods for measuring IMT and DC. Our findings indicate that MRI at 3 T is a feasible and promising tool for the comprehensive assessment of normal carotid geometry and function.

Original languageEnglish (US)
Pages (from-to)1470-1479
Number of pages10
JournalEuropean Radiology
Volume19
Issue number6
DOIs
StatePublished - Feb 13 2009

Keywords

  • Atherosclerosis
  • Carotid arteries
  • Distensibility
  • Intima-media thickness
  • MRI
  • Ultrasound
  • Wall imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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