Case study 3: Fragment hopping to design highly potent and selective neuronal nitric oxide synthase inhibitors

Haitao Ji*, Richard B. Silverman

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations
Original languageEnglish (US)
Title of host publicationScaffold Hopping in Medicinal Chemistry
Publisherwiley
Pages279-296
Number of pages18
Volume58
ISBN (Electronic)9783527665143
ISBN (Print)9783527333646
DOIs
StatePublished - Nov 1 2013

Keywords

  • Cerebral palsy
  • Fragment hopping
  • Fragment-based drug design
  • Inhibitor
  • Lead generation
  • Neuronal nitric oxide synthase
  • Selectivity

ASJC Scopus subject areas

  • Medicine(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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