TY - JOUR
T1 - Catalyst discovery through megalibraries of nanomaterials
AU - Kluender, Edward J.
AU - Hedrick, James L.
AU - Brown, Keith A.
AU - Rao, Rahul
AU - Meckes, Brian
AU - Du, Jingshan S.
AU - Moreau, Liane M.
AU - Maruyama, Benji
AU - Mirkin, Chad A.
N1 - Funding Information:
This material is based on work supported by the Sherman Fairchild Foundation, Inc.; Air Force Office of Scientific Research Award FA9550-16-1-0150; Air Force Research Laboratory Agreement FA8650-15-2-5518; and Air Force Office of Scientific Research Laboratory Research Independent Research Grant 16XCOR322. Research reported in this publication was also supported by National Cancer Institute of the NIH Award U54CA199091. We acknowledge additional support from the Vannevar Bush Faculty Fellowship Program sponsored by the Basic Research Office of the Assistant Secretary of Defense for Research and Engineering and funded by Office of Naval Research Grant N00014-15-1-0043. J.L.H. and L.M.M. acknowledge support from the Department of Defense through the National Defense Science & Engineering Graduate Fellowship Program. This work utilized the Northwestern University Micro/Nano Fabrication Facility and the Electron Probe Instrumentation Center Facilities of the Northwestern University Atom and Nanoscale Chacterization Experimental Center, which are partially supported by Soft and Hybrid Nanotechnology Experimental Resource NSF Grant ECCS-1542205, Materials Research Science and Engineering Center Grant DMR-1720139, and the State of Illinois. The US Government is authorized to reproduce and distribute reprints for governmental purposes notwithstanding any copyright notation thereon.
Funding Information:
ACKNOWLEDGMENTS. This material is based on work supported by the Sherman Fairchild Foundation, Inc.; Air Force Office of Scientific Research Award FA9550-16-1-0150; Air Force Research Laboratory Agreement FA8650-15-2-5518; and Air Force Office of Scientific Research Laboratory Research Independent Research Grant 16XCOR322. Research reported in this publication was also supported by National Cancer Institute of the NIH Award U54CA199091. We acknowledge additional support from the Vannevar Bush Faculty Fellowship Program sponsored by the Basic Research Office of the Assistant Secretary of Defense for Research and Engineering and funded by Office of Naval Research Grant N00014-15-1-0043. J.L.H. and L.M.M. acknowledge support from the Department of Defense through the National Defense Science & Engineering Graduate Fellowship Program. This work utilized the Northwestern University Micro/Nano Fabrication Facility and the Electron Probe Instrumentation Center Facilities of the Northwestern University Atom and Nanoscale Chacterization Experimental Center, which are partially supported by Soft and Hybrid Nanotechnology Experimental Resource NSF Grant ECCS-1542205, Materials Research Science and Engineering Center Grant DMR-1720139, and the State of Illinois. The US Government is authorized to reproduce and distribute reprints for governmental purposes notwithstanding any copyright notation thereon.
Publisher Copyright:
© 2019 National Academy of Sciences. All Rights Reserved.
PY - 2019/1/2
Y1 - 2019/1/2
N2 - The nanomaterial landscape is so vast that a high-throughput combinatorial approach is required to understand structure–function relationships. To address this challenge, an approach for the synthesis and screening of megalibraries of unique nanoscale features (>10,000,000) with tailorable location, size, and composition has been developed. Polymer pen lithography, a parallel lithographic technique, is combined with an ink spray-coating method to create pen arrays, where each pen has a different but deliberately chosen quantity and composition of ink. With this technique, gradients of Au-Cu bimetallic nanoparticles have been synthesized and then screened for activity by in situ Raman spectroscopy with respect to single-walled carbon nanotube (SWNT) growth. Au3Cu, a composition not previously known to catalyze SWNT growth, has been identified as the most active composition.
AB - The nanomaterial landscape is so vast that a high-throughput combinatorial approach is required to understand structure–function relationships. To address this challenge, an approach for the synthesis and screening of megalibraries of unique nanoscale features (>10,000,000) with tailorable location, size, and composition has been developed. Polymer pen lithography, a parallel lithographic technique, is combined with an ink spray-coating method to create pen arrays, where each pen has a different but deliberately chosen quantity and composition of ink. With this technique, gradients of Au-Cu bimetallic nanoparticles have been synthesized and then screened for activity by in situ Raman spectroscopy with respect to single-walled carbon nanotube (SWNT) growth. Au3Cu, a composition not previously known to catalyze SWNT growth, has been identified as the most active composition.
KW - Carbon nanotube growth
KW - Catalysis
KW - Combinatorial screening
KW - In situ Raman spectroscopy
KW - Multimetallic nanoparticle synthesis
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U2 - 10.1073/pnas.1815358116
DO - 10.1073/pnas.1815358116
M3 - Article
C2 - 30559201
AN - SCOPUS:85058889650
SN - 0027-8424
VL - 116
SP - 40
EP - 45
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
IS - 1
ER -