Catalytic enantioselective α-acylvinyl anion reactions of silyloxyallenes

Troy E. Reynolds*, Karl A. Scheidt

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

(Chemical Equation Presented) Alternatives with silicon: The enantioselective Lewis acid catalyzed addition of racemic silyloxyallenes to aldehydes is reported. A {(salen)CrIII} complex efficiently catalyzes the reaction of these α-acylvinyl anion equivalents (see scheme) with excellent enantioselectivity, high yield, and superb control over the configuration of the resulting double bond.

Original languageEnglish (US)
Pages (from-to)7806-7809
Number of pages4
JournalAngewandte Chemie - International Edition
Volume46
Issue number41
DOIs
StatePublished - 2007

Keywords

  • Acylvinyl anions
  • Asymmetric catalysis
  • Chromium
  • Silicon
  • Synthetic methods

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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