Catecholamines

Lewis Landsberg*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Norepinephrine (NE), epinephrine (E), and dopamine are the naturally occurring biologically important catecholamines. E is the circulating hormone of the adrenal medulla, regulated by impulse traffic in the splanchnic nerves; NE is the adrenergic neurotransmitter released from peripheral sympathetic nerve endings in response to a downward flow of impulses from the sympathetic centers in the brainstem; and DA is formed in peripheral tissues from the decarboxylation of circulating DOPA. The physiologic effects of the catecholamines are mediated by cell surface receptors on effector cells. The excessive production of these compounds in pheochromocytomas and paragangliomas is responsible for the clinical manifestations of these tumors.

Original languageEnglish (US)
Title of host publicationContemporary Endocrinology
PublisherHumana Press Inc
Pages1-14
Number of pages14
DOIs
StatePublished - Jan 1 2018

Publication series

NameContemporary Endocrinology
ISSN (Print)2523-3785
ISSN (Electronic)2523-3793

Keywords

  • Adrenal medulla
  • Dopamine
  • Epinephrine
  • Norepinephrine
  • Sympathetic nervous system

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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  • Cite this

    Landsberg, L. (2018). Catecholamines. In Contemporary Endocrinology (pp. 1-14). (Contemporary Endocrinology). Humana Press Inc. https://doi.org/10.1007/978-3-319-77048-2_1