Catheter-directed MR angiography and cross-sectional imaging for the assessment of renal artery stenosis

Reed A. Omary*, Brian E. Schirf, Jordin D. Green, Yashpal S. Kanwar, Steven M. Shea, Timothy J Carroll, James Carr, Debiao Li

*Corresponding author for this work

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

PURPOSE: Catheter-directed intraarterial (IA) gadolinium (Gd)-enhanced gradient-echo (GRE) imaging has been used in the setting of magnetic resonance (MR) imaging-guided endovascular procedures for two-dimensional (2D) or three-dimensional (3D) depiction of blood vessels. In a swine model, the hypothesis was tested that the combination of 2D IA GRE and 2D cross-sectional steady-state free precession (SSFP) imaging improves assessment of renal artery stenosis (RAS) compared with 3D IA GRE imaging alone. MATERIALS AND METHODS: Bilateral RAS was surgically induced in seven pigs. Detection of stenoses was then compared between the combination of 2D projection IA GRE and cross-sectional 2D SSFP imaging without contrast agent and 3D IA GRE alone. Radiographic digital subtraction angiography (DSA) was employed as the reference standard. Linear regression was used to compare stenosis measurements, with an α of 0.05. RESULTS: Radiographic DSA and MR imaging were successful in the seven animals (14 stenoses). With use of linear regression analysis, the combination of 2D IA GRE and 2D SSFP imaging had a higher r2 (0.87 vs 0.72) and a slope closer to unity (1.02 vs 0.77) compared with 3D IA GRE imaging alone. When comparing intercepts, the regression line for SSFP significantly differed from that of 3D IA GRE imaging (P < .05). CONCLUSION: The combination of 2D IA GRE and cross-sectional 2D SSFP imaging improves the accuracy of RAS detection compared with IA 3D IA-GRE alone.

Original languageEnglish (US)
Pages (from-to)255-260
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Volume16
Issue number2 I
DOIs
StatePublished - Jan 1 2005

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Catheter-directed MR angiography and cross-sectional imaging for the assessment of renal artery stenosis'. Together they form a unique fingerprint.

  • Cite this