Caught by a masquerade: Sclerosing orbital inflammation

Jennifer E. Thorne, Nicholas J. Volpe*, Allan E. Wulc, Steven L. Galetta

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

21 Scopus citations


Idiopathic sclerosing inflammation of the orbit is a distinct form of orbital inflammatory disease characterized by slow and relentless involvement of orbital structures. It is this insidious and relentless course that makes distinction from neoplastic lesions clinically difficult. We report the case of a patient with a several-week history of headache and decreased vision that was originally thought to represent an optic nerve sheath meningioma, based on clinical and radiographic evaluation. Subsequent histopathology from an optic nerve biopsy, however, was more consistent with optic nerve glioma. Eventually, pathologic examination of whole sections through the optic nerve was required to establish and confirm the actual diagnosis of sclerosing orbital inflammation.

Original languageEnglish (US)
Pages (from-to)50-54
Number of pages5
JournalSurvey of ophthalmology
Issue number1
StatePublished - Jan 1 2002


  • Computed tomography
  • Histopathology
  • Optic nerve glioma
  • Optic nerve sheath meningioma
  • Sclerosing orbital inflammation
  • Sclerosing pseudotumor

ASJC Scopus subject areas

  • Ophthalmology


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