Caution Needed

Molecular Diagnosis of Pediatric Group A Streptococcal Pharyngitis

Robert R Tanz, Xiaotian Zheng, Donna M. Carter, Molly C. Steele, Stanford T Shulman

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Among throat swabs processed in the microbiology laboratory as back-up for negative rapid antigen detection test results, we found a significant increase in the proportion that tested positive for group A streptococci after changing from throat culture to a molecular test.For group A streptococcus testing, our hospital laboratory replaced throat cultures with a stand-alone molecular diagnostic test that takes no more than 1 hour to perform. The prevalence of positive laboratory test results increased significantly (P < .0001) after the change to molecular testing, probably because of the extreme sensitivity of the molecular test.

Original languageEnglish (US)
Pages (from-to)e145-e147
JournalJournal of the Pediatric Infectious Diseases Society
Volume7
Issue number3
DOIs
StatePublished - Aug 17 2018

Fingerprint

Pharyngitis
Pharynx
Pediatrics
Streptococcus
Hospital Laboratories
Molecular Pathology
Microbiology
Routine Diagnostic Tests
Antigens

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases

Cite this

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abstract = "Among throat swabs processed in the microbiology laboratory as back-up for negative rapid antigen detection test results, we found a significant increase in the proportion that tested positive for group A streptococci after changing from throat culture to a molecular test.For group A streptococcus testing, our hospital laboratory replaced throat cultures with a stand-alone molecular diagnostic test that takes no more than 1 hour to perform. The prevalence of positive laboratory test results increased significantly (P < .0001) after the change to molecular testing, probably because of the extreme sensitivity of the molecular test.",
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Caution Needed : Molecular Diagnosis of Pediatric Group A Streptococcal Pharyngitis. / Tanz, Robert R; Zheng, Xiaotian; Carter, Donna M.; Steele, Molly C.; Shulman, Stanford T.

In: Journal of the Pediatric Infectious Diseases Society, Vol. 7, No. 3, 17.08.2018, p. e145-e147.

Research output: Contribution to journalArticle

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AU - Shulman, Stanford T

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