Cavernous sinus syndrome due to prolactinoma: Resolution with bromocriptine

Lucille W. King, Mark E. Molitch*, John W. Gittinger, Samuel M. Wolpert, Jack Stern

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Cavernous sinus syndrome due to a pituitary tumor is quite rare. Our patient had a large prolacinoma that extended superiorly, causing bitemporal visual field defects, and laterally into the right cavernous sinus, causing tearing, dysesthesia in the distribution of the fifth cranial nerve, a loss of the corneal reflex, and a sixth cranial nerve palsy. Prolactin levels ranged between 800 and 1000 ng/mL. Treatment with 7.5 mg of bromocriptine daily caused a marked reduction in the size of the tumor and resolution of her visual field defects and cranial nerve dysfunction over 6 months. We feel that bromocriptine should be considered as initial therapy for patients with prolactinomas extending into the middle or posterior cranial fossae.

Original languageEnglish (US)
Pages (from-to)280-284
Number of pages5
JournalSurgical Neurology
Issue number3
StatePublished - Mar 1983


  • Bromocriptine
  • Cavernous sinus syndrome
  • Prolactin
  • Prolactinoma

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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