Abstract
Transient CD154 blockade at the onset of Theiler's murine encephalomyelitis virus-induced demyelinating disease ameliorated disease progression for 80 days, reduced immune cell infiltration, and transiently increased viral loads in the central nervous system. Peripheral antiviral and autoimmune T-cell responses were normal, and disease severity returned to control levels by day 120.
Original language | English (US) |
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Pages (from-to) | 2247-2250 |
Number of pages | 4 |
Journal | Journal of virology |
Volume | 77 |
Issue number | 3 |
DOIs | |
State | Published - Feb 2003 |
ASJC Scopus subject areas
- Insect Science
- Virology
- Microbiology
- Immunology