CD5+ immunophenotype in the bone marrow but not in the peripheral blood in a patient with hairy cell leukemia

Lydia Usha*, Basil Bradlow, Wendy Stock, Leonidas C. Platanias

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We report the case of a patient with rare CD5+ hairy cell leukemia, which was unusual, as there was also a discrepancy between the bone marrow and peripheral blood immunophenotypes. We propose that some degree of maturation within the malignant clone and the predominance of more mature CD5- hairy cells in the peripheral blood can explain this observation. The patient was treated with a conventional course of cladribine (2'- chlorodeoxyadenosine) and achieved complete remission. We conclude that the unusual CD5+ immunophenotype of this patient did not affect prognosis or change the response to standard therapy. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)210-213
Number of pages4
JournalActa Haematologica
Volume103
Issue number4
DOIs
StatePublished - 2000

Keywords

  • Hairy cell leukemia
  • Immunophenotype

ASJC Scopus subject areas

  • Hematology

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