Cell-free biomanufacturing

Bradley C. Bundy; J. Porter Hunt; Michael C. Jewett; James R. Swartz; David W. Wood; Douglas D. Frey; Govind Rao

doi:10.1016/j.coche.2018.10.003

Cell-free biomanufacturing

Bradley C. Bundy, J. Porter Hunt, Michael C. Jewett, James R. Swartz, David W. Wood, Douglas D. Frey, Govind Rao

Chemical and Biological Engineering

Research output: Contribution to journal › Review article

13 Scopus citations

Abstract

Since its early development and use to decipher the genetic code, in vitro or ‘cell-free’ systems have been used as an important research tool to understand biochemical mechanisms and metabolic pathways. More recently, due to important engineering advances the technology is rapidly becoming a biomanufacturing platform for protein therapeutics, vaccines, enzyme biocatalysts, fuels, and commodity chemicals. Here we report recent applications and advances in the cell-free biomanufacturing field and the potential of this emerging approach.

Original language	English (US)
Pages (from-to)	177-183
Number of pages	7
Journal	Current Opinion in Chemical Engineering
Volume	22
DOIs	https://doi.org/10.1016/j.coche.2018.10.003
State	Published - Dec 2018

ASJC Scopus subject areas

Energy(all)

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10.1016/j.coche.2018.10.003

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Bundy, B. C., Hunt, J. P., Jewett, M. C., Swartz, J. R., Wood, D. W., Frey, D. D., & Rao, G. (2018). Cell-free biomanufacturing. Current Opinion in Chemical Engineering, 22, 177-183. https://doi.org/10.1016/j.coche.2018.10.003

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AU - Bundy, Bradley C.

AU - Hunt, J. Porter

AU - Jewett, Michael C.

AU - Swartz, James R.

AU - Wood, David W.

AU - Frey, Douglas D.

AU - Rao, Govind

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