Abstract
Phytohemagglutinin induced lymphocyte deoxyribonucleic acid synthesis, dermal hypersensitivity, and peripheral blood thymus derived lymphocyte numbers were assessed in 9 men with experimentally induced rubella infection. Five of these men and 2 additional volunteers received treatment with tilorone dihydrochloride, an antiviral drug. Response to phytohemagglutinin was not changed during rubella; T lymphocyte numbers in peripheral blood were not influenced by the viral illness. However, dermal hypersensitivity was markedly impaired in all volunteers during the height of the illness. Tilorone alone, or with rubella, had no effect on any of the parameters studied.
Original language | English (US) |
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Pages (from-to) | 212-215 |
Number of pages | 4 |
Journal | Infection and immunity |
Volume | 10 |
Issue number | 1 |
DOIs | |
State | Published - 1974 |
ASJC Scopus subject areas
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases